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Iron chelators, such as DFP, DFX, and DFO, have been shown to significantly reduce iron overload and serum iron levels in patients with thalassaemia [113,114,115]

Pharmazie 60 6265

At that time, Coleys work illuminated the potential role of the immune system in combating malignancies, laying the foundation for contemporary cancer immunotherapy

These effects are likely to be mediated through the regulation of MG levels, as MG was demonstrated to act as a competitive partial agonist for GABAA (-aminobutyric acid A) receptors (Distler et al., 2012