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As a close structural relative of GHK-Cu (Gly-His-Lys), AHK-Cu shares the copper-chelating tripeptide architecture but exhibits a distinct biological activity profile studied particularly in the contexts of hair follicle biology, angiogenesis, and skin extracellular matrix research

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Amelioration of Cyp7a1 and G6pc by fat transplantation in Insr P1195L/ +/HFD liver and suppression of Cyp7a1 by glycerol in wild-type mice suggest that suppressed hepatic expression of Cyp7a1 might well play a role in the regulation of glucose homeostasis in Insr P1195L/ +/HFD mice

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