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Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity

Priority should also be given to studies that apply standardised outcome measures, including UPDRS with MCID reporting, DAT imaging, and validated oxidative stress biomarkers

Trypsin was neutralized with 500 l complete medium, the cells were resuspended and 100 l of the suspension was mixed with 6.9 ml Beckman Coulter Isoton II diluent (Fisher Scientific, NC2470899) for counting with a Beckman Coulter Z1 Coulter Cell Particle counter

The generalizability of findings is further constrained by heterogeneity in study populations, supplementation protocols, dosage forms, and outcome measures