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Regarding altered neuronal/synaptic activity, a reduced glutamatergic projection from ACC to the ventral hippocampal CA1 area is suggested to contribute to depressive-like symptoms in 3-month-old 5xFAD mice (Kim et al., 2023)

High endothelial STING expression is associated with a reduced incidence of lymphovascular infiltration within tumor tissue, increased CD8 + T cell infiltration, and a favorable prognosis in cancers [129]