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Yao XM, Tang JH, Zhu H, Jing Y

10.1016/j.cell.2005.01.027

Ionotropic Glutamate Receptors Since NMDA receptors mediate the transfer of Na + into cells, there is a possibility that they represent, in addition to glutamate transporters and metabotropic receptors, another mechanism responsible for the cytotoxic swelling activated by increased glutamate concentrations (Winkler et al., 2016)

Intriguingly, evidence for neuroprotection in other neurologic diseases from the classic and modified KD has been reported in pilot clinical studies and in pre-clinical laboratory models, as described below and summarized in Tables 1, 2