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One of the best-replicated brain findings from subjects with ASD is an early-accelerated brain volume growth

Studies indicate that A1AT therapy can lead to a reduction in systemic inflammation, as measured by lower CRP levels, thus potentially decreasing the overall inflammatory burden on the lungs (68) Moreover, the reduction in inflammatory markers can also be indicative of the therapys effectiveness in mitigating the proteolytic damage caused by neutrophil elastase, which is typically unopposed in AATD patients due to low A1AT levels

Yan H, Zhu H, Shen J (2007) Molecular dynamics simulation study on zwitterionic structure to maintain the normal conformations of Glutathione