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These deposits disrupt the structure and function of cells 9

doi: 10.3389/fbioe.2023.1161472 Received 08 February 2023 Accepted 24 February 2023 Published 10 March 2023 Volume 11 - 2023 Edited by Wen Sun, Dalian University of Technology, China Reviewed by Xin Liu, The University of Chicago, United States Xiaobo Wang, Fourth Military Medical University, China Updates Copyright 2023 Liu, Hao, Liu and Hu

Key bottlenecks, including the lack of standardized protocols, limited inter-laboratory harmonization, insufficient regulatory frameworks for biomarker validation, and challenges in biological interpretation, must be systematically addressed

This might be attributed to localisation of the inflammation to the intestine in CD causing alteration of the DMET protein abundances