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Explain realistic treatment expectations, likely aftercare needs and limits of online theory to clients

APOE4 impairs astrocytic clearance of extracellular Tau, leading to pathogenic Tau accumulation (Eisenbaum et al., 2024)

Activating Nrf2 thus offers a dual benefit: it strengthens anti-ferroptotic defenses while actively supporting therapies designed to raise native FXN levels

Ethics approval and consent to participate The study was conducted under protocols approved by the Scientific Research Committee of the Universidad Industrial de Santander and complied with the Colombian Medical Code of Ethics, which is in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki