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doi:10.3390/s130810823

A 2025 UCSF open-label pilot in Parkinsons disease, the first test of a psychedelic in a neurodegenerative disease, found that two sessions improved mood, cognition, and motor symptoms for weeks to months, with a larger randomized trial now under way

Clinical trials show tirzepatide produces 22.5% average weight loss compared to semaglutides 14.9%, likely because activating both incretin pathways provides more comprehensive metabolic regulation than activating one pathway alone

In addition to SF, other ITC and ITC-rich plants have also demonstrated consistent benefits in ameliorating AD-related pathology