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Unlike prior studies implicating exosomes, microvesicles, or small EVs [56, 57], we identify a unique EV subtype, i.e., LG-EVs, whose macropinocytic uptake drives SFR of HCC (Fig

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Specifically, U937 cells were stimulated (or not) with LPS (100 ng/ml) for 30 min at 37 C

Conclusion: Treatment regimens for late cellular rejection, chronic ductopenic rejection, and antibody mediated rejection are variable with a wide range of response rates