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Distribution of cystine/glutamate exchange transporter, system x(c)-, in the mouse brain

L-carnitine is a naturally occurring amino acid derivative synthesized primarily in the liver and kidneys from the essential amino acids lysine and methionine

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Additionally, there is now accumulating evidence that NAFLD adversely affects not only the coronary arteries (promoting accelerated coronary atherosclerosis) but also all other anatomical structures of the heart, conferring an increased risk of cardiomyopathy (mainly left ventricular diastolic dysfunction and hypertrophy, leading to the development of congestive heart failure), cardiac valvular calcification (mainly aortic-valve sclerosis), cardiac arrhythmias (mainly atrial fibrillation) and some cardiac conduction defects