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The mechanisms that keep CpG islands free of methylation appear to involve binding of transcription factors and other transcriptional machinery or the act of transcription itself

GLP-1 agonists slow gastric emptying and affect appetite through gut-brain signaling

The manipulation of transcription factors may also have utility as a potential therapeutic in neurodegenerative conditions and in preventing neuronal impairment associated with aging

Thus, it can be hypothesized that the ability of DSIP to maintain efficiency of oxidative phosphorylation, even in the setting of hypoxia, could make the peptide a subject of interest for conditions such as stroke and heart attack in future research