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Recently, a multinational study, the Study of Acute Liver Transplantation (SALT)[86], identified cases where drug exposure, specifically nonsteroidal anti-inflammatory drugs (NSAIDs) and paracetamol, had led to acute liver failure and resultant registration for liver transplantation

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ROS also contribute to TNF-induced IL-6 expression and NF-B activation (Pearlstein et al., 2002)