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According to a recent study, the combination of chemical treatment with an FMD reduces the expression of heme oxygenase-1 (HO-1), which is a stress-responsive enzyme that protects cancer cells against oxidative damage and apoptosis in vivo

To our knowledge, many studies have been carried out in loading of cancer drugs, such as doxorubicin and camptothecin, onto GO functionalised with an antibody for theranostic of cancer cells 42,43

The low-energy sensors, sirtuin-1 (SIRT1) and adenosine monophosphate-activated protein kinase (AMPK) are known to be involved

Due to the multidimensionality of first- and second-order data, these response patterns were processed by PCA/UPCA, which allows to assess whether the analysed data contains the discriminatory information required for identification purposes [36]