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Importantly, VEGFA hyper mice developed in an agedependent progressive manner cataracts whose agerelated onset and increase in severity resembled aspects of human agerelated cataracts (Fig 3BG), which represent the most frequent form of cataracts and the most common cause of reversible blindness (Rao et al , 2011

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These medications also target the endocrine system to reduce insulin resistance, lower fasting glucose levels, and signal that the body is no longer in crisis mode