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doi:10.1378/chest.11-2300

Flux Balance Analysis (FBA) is a mathematical approach to predict the flow of metabolites through a GSM model with a specific goal/objective, typically maximizing of growth/biomass

Chromates are frequent water contaminants in many regions of the world

Initially, it was shown to induce detoxifying and antioxidant enzymes in the liver, which consequently mediates the detoxification and clearance of carcinogens and reactive oxygen species to elevate cell defense ( 3.1 SFN and fatty liver disease Fatty liver disease (FLD) is a common liver disease around the world with a broad spectrum from simple steatosis to steatohepatitis, fibrosis, and cirrhosis, and is characterized by excessive lipid accumulation in the liver ( SFN was first reported to activate Nrf2 and prevent liver X receptor- (LXR) agonist-induced hepatic lipogenesis and steatosis by activating farnesoid X receptor (FXR) and inducting small heterodimer partner in mice in 2011 (Zhou et al., 2014