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the level of said marker is determined by means of a separation technique coupled to a method for identification and quantification of the polar metabolite

Different from regular cancer cells, CSCs have a lower level of ROS, which might contribute to a slower growth rate, reduced oxidative metabolism, and elevated expression of the ROS scavenging system (Recalcati et al., 2019

Set7/9 methylates the FOXO3 protein It was shown that Set7/9 methylates FOXO3 at lysine 270 (K270) in vitro and in vivo and this modification leads to the inhibition of its DNAbinding activity and subsequent transactivation of the target genes 88

During the pathological progression of DM, four classes of critical microbial metabolites (SCFAs, BCAAs, bile acids, bacterial endotoxins) mediate multi-organ damage through the gut-lung axis (Saad et al., 2016)