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Results: Percentage or median (range) values for the entire cohort (N=141) at baseline visit: age 16.3 years (6.5-25.6), 61% male, 89% White, 81% large duct PSC, 75% w/ IBD, length of time from PSC diagnosis 2.6 years (0.1-20.8), absence of pruritus 90%, AST 35 U/L (13-733), ALT 37 U/L (9-816), bilirubin 0.6 mg/dL (0.2-62), alk