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In: 3rd symposium on systematic reviews: beyond the basics

Figure 3 In GBM, the role of glutaminolysis depends not only on how glutamine is used but also on the enzymes and transporters that help bring it into the cell and break it down

As illustrated in Figure 1 , these alterations in the epigenetic landscape, characterized by global genomic DNA hypomethylation and specific genes promoter hypermethylation, both contribute to the pathogenesis and development of ESCC via distinct mechanisms [25]