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Blood samples were collected at the following time points in each cycle: 24 h, 12 h, and 0 h before dosing, and 5 min, 10 min, 15 min, 20 min, 30 min, 45 min, 1 h, 1.25 h, 1.5 h, 1.75 h, 2 h, 2.5 h, 3 h, 3.5 h, 4 h, 5 h, 6 h, 8 h, 12 h, and 24 h after dosing, totaling 23 collection points