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They induce dysfunction in brain areas implicated in emotional and behavioral regulation and cognition (such as the prefrontal cortex, basal ganglia) and fear and anxiety-related regions (such as the amygdala, insula and anterior cingulate cortex) (67)

A 2023 systematic review and meta-analysis that evaluated a total of 1020 patients participating in 14 RCTs found that acupuncture significantly regulated TPOAb and TGAb and hormones (FT3, FT4, TSH) compared to levothyroxine alone (83)