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Functionally, glutathione was essential for melatonin-mediated immunosuppression, as IKE co-treatment abolished the reductions in IL-5, IL-13, and IL-4 production observed with melatonin alone ( Figures 8FH )

PMID: 36334726 ACS Environ Au Machine Learning-Assisted Recognition of Environmental Sulfur-Containing Chemicals in Nontargeted Mass Spectrometry Analysis of Inadequate Mass Resolution

702 Mutations in IDH impair its ability to catalyze the conversion of isocitrate to -KG and instead confer neomorphic activity, whereby it reduces -KG to D-2-hydroxyglutarate (D-2HG) in an NADPH-dependent manner

[2] Useful metabolites are excluded since they are polar, and in general contain one or more charged groups