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doi: 10.3390/cimb45120588

ISSN 1027-5606

These proteins are integral to chromatin structure and gene regulation, and their interaction with small peptides may influence epigenetic mechanisms

Based on this, it has been confirmed that prescribing lenalidomide with EGFRvIII-CAR-T cells elevated the F-actin polymerization and the CAR-T cell infiltration and cytotoxicity in the tumor site of the glioblastoma murine model, leading to prolonged survival of treated mice [114]