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Continued monitoring and additional studies are essential to fully understand the long-term safety and efficacy of this therapy ( In this review, we provide an up-to-date understanding of the molecular mechanisms and regulatory pathways involved in A1AT immunomodulatory actions, as well as its homeostatic functions in metal and lipid metabolism

Healy, D., Bahrick, A., Bak, M., Barbato, A., Calabr, R

doi: 10.1016/j.fochx.2023.100871

Moreover, the IL-21 receptor exerts neuroprotective effects in IS mice ( 2.3 Immune organ responses after an ischemic stroke Immune-related organs include the spleen, bone marrow, thymus, lymph nodes, lungs, liver, adrenal glands, and gut (69)