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Trimethylamine N-oxide promotes ApoE -/- mice atherosclerosis by inducing vascular endothelial cell pyroptosis via the SDHB/ROS pathway

The primary role of glutathione is to protect your mitochondria

Moreover, high -tocopherol levels could suppress the tumor inhibitory effect of - and -tocopherols by competing for their binding to the proteins required for chemopreventive effect [97]

Prolonged metabolic stress impairs mitophagy and reduces mitochondrial function, as indicated by decreased oxidative phosphorylation, impaired ATP synthesis, and elevated reactive oxygen species (ROS) generation ( Hepatic lipid overload can also directly initiate inflammatory signaling by activating resident immune cells