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Article views(450) PDF downloads(260) / Placental poor vascularization in sows is associated with insufficient placental Pro abundance Dietary Pro deprivation during pregnancy exacerbates nutritionally restricted-induced pregnancy impairment and impaired placental angiogenesis Pro depends on VEGF-A and bFGF expression to support angiogenesis Phosphorylated p-STAT3Tyr705-bFGF/VEGF-A pathway mediates Pro promotion of placental angiogenesis Pro improves mtROS homeostasis to maintain p-STAT3Tyr705-bFGF/VEGF-A pathway Pro regulates mtROS homeostasis and angiogenesis via PRODH catabolic pathway and gestational nutritional restriction Pro-PRODH catabolism maintain mtROS homeostasis in Sirt1-SOD2-dependent pathway