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The treatment can be repeated when benefits begin to diminish, making it a sustainable long-term option for managing bone-on-bone knee pain.

To simultaneously quantify the levels of persulfide and polysulfide sulfur, one aliquot of reaction mixture (100 L) was blocked with IAM-TPP (1 mM) for procedure A and another aliquot of the same reaction (100 L) was blocked with IAM (1 mM) for procedure B for 20 min at RT protected from light

Intracellular GSH and GSSG levels were corrected for intracellular protein, determined by Pierce BCA Protein Assay Kit (Thermo Fisher Scientific, 23225) using albumin as a standard

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