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Additionally, co-transplantation with stroma can selectively influence the expression of homing receptors and ultimately improve engraftment, as hematopoietic activity increases considerably after stromal establishment (Flake and Zanjani, 2016)

Efficacy and safety of combined deferiprone and deferasirox in iron-overloaded patients: a systematic review

Furthermore, according to a randomized trial conducted in a population of patients with T2D receiving metformin for at least 4 years and experiencing diabetic neuropathy, administration of 1 mg oral methylcobalamin for 1 year was associated with a significant improvement in neurophysiological parameters and scores assessing neuropathic pain and quality of life [58]

Folate deficiency also leads to diarrhea, loss of appetite, and weight loss