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More recently, DddA-derived cytosine base editors (DdCBEs) have further enhanced the precision of mtDNA editing by enabling C-to-T conversions without generating double-strand breaks, thereby providing a new toolkit for the direct correction of mutant mitochondrial genomes [547]

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Marucci G, Buccioni M, Ben DD, Lambertucci C, Volpini R, Amenta F (2021) Efficacy of acetylcholinesterase inhibitors in Alzheimers disease