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Preclinical safety data does not always predict human safety outcomes, and the absence of adverse effects in controlled animal studies does not guarantee the same in diverse human populations with varying health conditions and concurrent medications

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Results from this study suggest that hepatic fat export in periparturient dairy cows is improved by choline supplementation during the transition period and this may potentially decrease the risk for metabolic disorders in the periparturient dairy cow. [7] Choline is also known to be involved in the synthesis of carnitine, cell membrane phospholipids, and the neurotransmitter acetylcholine

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