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Description

Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart

People may take oral supplements or receive clinician-directed treatment for different reasons, but the evidence, safety considerations and possible interactions can vary according to the product, dose and route of administration

Enrollment was halted for futility at a prespecified interim analysis as all 10 treated patients experienced rapid disease progression

Appl Physiol Nutr Metab 32(6):11241131 Gomez-Cabrera MC, Via J, Ji LL (2009) Interplay of oxidants and antioxidants during exercise: implications for muscle health