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Source quality and peptide purity matter enormously here

In 2017, Tang's group showed that heat shock 70-kDa protein 5 (HSPA5) negatively regulated ferroptosis in human pancreatic ductal adenocarcinoma (PDAC) cells through the HSPA5-GPX4 pathway (Zhu et al., 2017)

Among them, the best known ROS in human cells include superoxide anion (O 2 - ), which is the precursor of most other ROS, hydroxyl radical ( OH), peroxyl radical (ROO ), hydroperoxyl radical ( HO 2 ), and hydrogen peroxide (H 2 O 2 ), although the last one is not technically a free radical because it does not have unpaired electrons, but it represents a source of them [25] (Fig

32, 136147 10.1016/j.molmet.2019.12.003 [DOI] [PMC free article] [PubMed] [Google Scholar] 137.Zoncu R., Efeyan A