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Cellular alterations include increased lipid peroxides, elevated reactive oxygen species (ROS), and reduced Glutathione Peroxidase 4 (GPX4) levels (Fang et al., 2023) and depression (Song Y

Longer GAA repeats result in a more severe reduction in FXN expression (6595% decrease with respect to healthy controls) and are associated with early disease onset and greater disease severity (Figure 2)

In addition to being an antioxidant-rich food, dark chocolate is also swarming with cocoa flavonols that can improve cognitive function by reducing brain fog and fatigue15, and sharpening concentration

and (6) mirror plot showing the similarity between MS/MS spectra from the chemical standards versus mouse tissues