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Emerging pieces of evidence have suggested that miRNAs are deregulated in almost all human cancers, and found to involve in a wide spectrum of cancer hallmarks, such as sustained proliferative signaling, evasion of growth suppressors, activated invasion and metastasis, replicative immortality, angiogenesis, resistance to cell death, and evasion of immune destruction (Van Roosbroeck and Calin, 2017)

Berberine positively influences lipid metabolism by lowering LDL cholesterol and triglycerides, and supports gut microbiota that produce beneficial short-chain fatty acids

doi:10.1016/j.plefa.2021.102376 McBurney, Michael I et al

Provide clients with hyperhomocysteinemia with individualized dietary guidelines for restoring normal plasma homocysteine levels