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Damage-associated molecular patterns (DAMPs) released from pyroptotic cells further promote neutrophil activation and NETosis, contributing to sustained inflammation ( The dual roles of NETosis NETosis represents a specialized form of neutrophil cell death triggered by cellular activation, in which neutrophils release web-like structures composed of DNA, histones, and antimicrobial proteins as a defense mechanism against infection

Eur J Appl Physiol Occup Physiol 1996;73:434-9

The list of ingredients are as follows:- 100 gms Animal bones (chicken knuckles, goat trotters) Water Pink Himalayan Salt Apple cider vinegar Optional Garlic and ginger Herbs like parsley and thyme Spices like clove, cinnamon, coriander seeds, and star anise

This change in particle size is likely due to the presence of both PEI and DNA, which is involved in association and dissociation of water molecules creating a hydration shell around MNPs