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However, the majority of recently developed SARMs have non-steroidal structures, which may be based on [22]: Aryl-propionamide (andarine, ostarine, RAD140) Bicyclic hydantoin (BMS-564,929) Quinolinones and tetrahydroquinoline analogs Benizimidazole, imidazolopyrazole, indole, and pyrazoline derivaties Aniline, diaryl aniline, and bezoxazepinones derivatives Regardless of structure, all SARMs work by interacting with the androgen receptors (ARs) in specific tissues, i.e., selectively, rather than activating ARs throughout the body

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These two processes are not mutually substitutive but instead operate at distinct stages of disease progression

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