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Acknowledgements The authors would like to thank every researcher that contributed to the better understanding of the IGF-I role both in physiological and pathological conditions

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Liposomal GSH appeared to be effective at two doses (500 and 1000 mg/d) and effects were seen as early as 1 week. Participants experienced a decrease in oxidative stress and improved immune function

DSIP has been shown in various studies to interact with these neurotransmitter systems, though whether this represents direct receptor binding, allosteric modulation, or indirect effects on neurotransmitter synthesis, release, or metabolism remains unclear