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2024 Jun 1 [cited 2025 Jul 22];36(24):2312939

Unlike DRP1-regulated mitophagy, these results suggest that MFN2-regulated mitophagy exhibits tumor-suppressive effects in PDAC

The generated ROS, in turn, induces mitochondrial DNA damage, contributing to oxidative stress (42, 48)

However, cryoablation has been used in younger patients for the ablation of tumors [29], vascular malformations [30] , and foci of cardiac arrhythmias [31]