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1,2 PD can be associated in some cases with co-existent Dupuytrens contracture (DC

Carnitine, thus, acts as a shuttle, ferrying fatty acids to the mitochondrial furnace, where they are oxidized to produce adenosine triphosphate (ATP), the body's primary energy currency

EC 1.2.1.47) oxidizes TMABA to -butyrobetaine (-BB) as shown for Pseudomonas sp

For example, patients with systemic primary carnitine deficiency (SPCD) have a deficiency in carnitine due to a mutation in the plasma membrane sodium-dependent high affinity carnitine transporter (OCTN2) that enables cellular carnitine uptake in the heart, muscle, and kidney