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Acknowledgements The figures include parts that were created using images from Servier Medical Art, which is licensed under a Creative Commons Attribution 3.0 Unported License and also www.freepik.com

Data were collected at room temperature using a beam of size 15 15 m with energy 12.65 keV and flux of 2 10 12 ph/s at the sample position

Nutrient deficiency Cell starvation is another method used to cause ECD

Biosens Bioelectron 85:6875 Li Z, Ni Y, Kokot S (2015) A new fluorescent nitrogen-doped carbon dot system modified by the fluorophore-labeled ssDNA for the analysis of 6-mercaptopurine and hg (II)