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Market in 2008 and is now available only as a compounded preparation

Additional therapeutic strategies, such as the use of proton pump inhibitors (e.g., esomeprazole) to limit intestinal iron absorption, are also under clinical investigation [112]

The overexpression of MRP1 representing the strength of cancer cells can be exploited as a weakness by some CS agents, such as verapamil, that specifically target this transporter