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It can cause uterine hypertrophy, also known as endometrial hyperplasia, which is what causes heavy menstrual bleeding or prolonged bleeding during menstruation

Kong N, Tao W, Ling X, Wang J, Xiao Y, Shi S, et al

Results: Thirty cases (4 definite, 14 highly likely, 12 probable) of AZ DILI were included

As illustrated in Figure 1, this integrated strategy demonstrates multi-target synergistic effects, significantly improving clinical response, endoscopic remission, and mucosal healing rates, while exhibiting a unique efficacy enhancement and toxicity reduction profile