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DeSantis TZ, Hugenholtz P, Larsen N, Rojas M, Brodie EL, Keller K, Huber T, Dalevi D, Hu P, Andersen GL

The complementary mechanisms work through multiple pathways: DSIP enhances delta wave sleep (the deepest restorative phase), regulates stress hormone rhythms including cortisol normalization, supports natural sleep-wake cycle optimization, and promotes recovery processes occurring during deep sleep stages

Most patients describe treatment as minimally painful, and all procedures are performed in-office without sedation or downtime

In health, postprandial glucose elevation triggers pancreatic beta-cell insulin secretion in a biphasic pattern, facilitating glucose uptake in skeletal muscle, adipose tissue, and hepatic suppression of gluconeogenesis