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In another study, it is reported that chronic treatment (3 months) of TQ lead to reduction of oxidative stress in MI and help to maintain the activity of antioxidant enzymes in isoproterenol-induced MI rat model (137)

Core metabolic disturbancesoxidative stress, mitochondrial dysfunction, and hypoxiainitiate neurological damage, while the hormonal system, centered on the HPA axis, amplifies and coordinates these effects

These findings provide a theoretical framework for identifying novel, symptom-specific therapeutic targets for pharmacological intervention

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