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Mol Cell (2021) 81(18):3691707

Mice were treated with drugs either by i.p

3,4 The pathological accumulation of SnCs not only amplifies age-related immunological alterations but also constitutes a key pathogenic driver of multiple age-associated comorbidities

Finally, in a small nonrandomized, unblinded, controlled study in 42 obese children (mean age, 8 years) with MAFLD, lifestyle recommendations combined with 600 mg/day of supplemental RRR --tocopheryl acetate for six months reduced markers of oxidative stress and liver dysfunction and improved insulin sensitivity and the profile of lipid in the blood, when compared to baseline