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L.LopezO.JacksonS.LyketsosC.JagustW.et al (2005)

Pedrera et al (135) validated the factors causing membrane rupture due to ferroptosis in cell models such as NIH-3T3, HT-1080, Mda-157 and H441 cells

Engineering intervertebral disc regeneration: biomaterials, cell sources and animal models

The authors concluded that glutathione, with or without vitamin C and NAC, was well tolerated but did not produce measurable therapeutic benefit in this cohort (Williams et al., 2025)