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niger (SH-1) by integrating multiple modules, including the NADPH regeneration engineering module, the glutaredoxin system, the GSH synthesis engineering module, and the transcription factor module

OS is characterized by a disequilibrium between the generation of reactive oxygen species (ROS) and the organisms capacity to neutralize these reactive intermediates or rectify the resultant damage

Appropriate candidates for this treatment include people with classic TN pain in whom medications are ineffective or not tolerated, individuals with atypical features or with a diagnosis of trigeminal neuropathy, and individuals who are not deemed to be surgical candidates after review with the neurosurgical team

& Platt, F