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6a,b), and was not affected by vCD44BP expression (Extended Data Fig

Oxidative DNA damage Reactive oxygen species, especially OH radical generated during oxidative stress, can react with and cause modifications in all the components of the DNA molecule (the purine and pyrimidine bases and deoxyribose sugar backbone), causing damage such as base or sugar lesions, single-strand breaks, double-strand breaks, abasic site formation and DNADNA or DNAprotein cross-links [3,53,75]

Certain supplements, like milk thistle, whey protein, N-Acetyl Cysteine (NAC), or turmeric, may help boost and maintain your levels, as well