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Two of three subjects who had insulin resistance at baseline showed normal insulin responsiveness at the end of the study, and highly sensitive C-reactive protein (hs-CRP, a marker of systemic inflammation) improved by a median of 25% among participants who showed clinical psoriasis improvement

The reaction was halted using a 2 N H 2 SO 4 solution, and the absorbance was measured at 450 nm using a CLARIOstar microplate reader (CLARIOstar, BMG LABTECH, Germany)

Nov 2021;72(7):879-891

An indirect evaluation can be made by measuring the levels of vitamin K-dependent coagulation factors, which are below 50% in the presence of vitamin deficiency