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Another study confirmed that asiaticoside reduces the levels of serum creatinine and urea nitrogen in renal ischemiareperfusion model rats, reduces renal tissue injury, activates silent information regulatory factor 1-forkhead box O3-PTEN-inducible kinase protein 1-E3 ubiquitin ligase pathway, promotes mitochondrial autophagy, and reduces renal injury caused by renal ischemiareperfusion